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Congenital Heart Defects Study: Investigating Patent Ductus Arteriosus (PDA) in Pembroke Welsh Corgis

Congenital heart defects occur in a variety of dog breeds, with the most common being the patent ductus arteriosus (PDA). Although this is a correctable disorder in most puppies, it requires surgery or a catheter-based procedure which can be expensive and is not without risk. Therefore, determining the genetic cause of PDA in dogs would be highly desirable so that dogs could be screened and the genetic mutation could be eventually bred out of the canine population. Corgis are a breed at increased risk for PDA’s so the goal of this study is to evaluate Corgis with and without PDA’s in order to identify the gene mutation for this heart problem.

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